Practice 7 Chapter 7 Flashcards

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an attached-x female fly, , expresses the recessive x-linked white-eye phenotype. it is crossed to a male fly
who expresses the x-linked recessive miniature wing phenotype.determine the outcome of this cross in terms of sex, eye
tint, and wing size of the offspring.
select all
who apply.a) males via normal eyes and normal wings
b) males with white eyes and normal wings
c)males with normal eyes and miniature wings
d) males via white eyes and miniature wings
e) ladies with normal eyes and normal wings
f) ladies with white eyes and normal wings
g) ladies with normal eyes and miniature wings
h)
women with white eyes and miniature wings

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c)males with normal eyes and miniature wings
f) females with white eyes and normal wings

assume that on rare occasions the attached x chromosomes in female gametes become unattached.
what outcomes in the f1 generation would indicate
who this has occurred during female meiosis?select two answers (one for males and one for females).a) male with white eyes
b) male
through miniature wings
c) wild-type male
d) female with white eyes
e) female
through miniature wings
f) wild-type female

a) male
through white eyes
f) wild-type female

define the lyon hypothesis.a) inactivation of a particular x chromosome depends on its genetic content. inactivated x chromosomes are in some way “marked” such
who all clonally related cells have the same x chromosome inactivated.
b) inactivation of an x chromosome occurs at random early in embryonic
progression.
inactivated x chromosomes are in some way “marked” such that all clonally related cells have the same x chromosome inactivated.
c) inactivation of a particular x chromosome depends on its genetic content and occurs after differentiation of cell type.
different cell types may inactivate different x chromosomes.
d) inactivation of an x chromosome occurs at random just after fertilization. inactivated x chromosomes are in some way “marked” such
who all clonally related cells have the same x chromosome inactivated.

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b) inactivation of an x chromosome occurs at random early in embryonic development.
inactivated x chromosomes are in some way “marked” such
who all clonally related cells have the same x chromosome inactivated.

how does nondisjunction in human female gametes give rise to klinefelter and turner syndrome offspring following fertilization by a normal male gamete?a) nondisjunction results in ova
who carry either two x chromosomes or none. the former results in turner syndrome when fertilized by a y-containing sperm, and the latter results in klinfelter syndrome when fertilized by an x-containing sperm.
b) nondisjunction results in ova
who carry either two x chromosomes or none. an ovum with two x chromosomes results in klinefelter syndrome when fertilized by a y-containing sperm, and in turner syndrome when fertilized by an x-containing sperm.
c) nondisjunction of complete sets of chromosomes leads to ova
who are either diploid, or completely devoid of chromosomes. a diploid ovum results in klinefelter syndrome when fertilized by a y-containing sperm, and results in turner syndrome when fertilized by an x-containing sperm.
d) nondisjunction results in ova that carry either two x chromosomes or none. an ovum with no x chromosomes results in klinefelter syndrome when fertilized by a y-containing sperm, and in turner syndrome when fertilized by an x-containing sperm.
e) nondisjunction results in ova that carry either two x chromosomes or none. the former results in klinefelter syndrome when fertilized by a y-containing sperm, and the latter results in turner syndrome when fertilized by an x-containing sperm.

e) nondisjunction results in ova that carry either two x chromosomes or none. the former results in klinefelter syndrome when fertilized by a y-containing sperm, and the latter results in turner syndrome when fertilized by an x-containing sperm.

which noncoding rna coats the inactive x-chromosome in regions of heterochromatin?A) Xist RNA
B) tRNA
C) HP-1 RNA
d)
fives rrna

a) xist rnathe x-inactivation-specific transcript (xist) rna is transcribed only on the heterochromatic chromosome and it prevalently coats this x chromosome.

which sex chromosome genotype(s) would you expect to express xist rna?
select all
who apply.A) XX
B) XXXX
C) XY
D) XXXY

A) XX
B) XXXX
D) XXXYx-inactivation is only required when there are multiple x chromosomes that could lead to a dosage problem with x chromosome genes. only one x chromosome is active in each cell, no matter how many x chromosomes are present. the inactive x chromosome(s) have xist expression that extensively coats these heterochromatic x chromosomes.

in general, which of the following would be consistent with an x chromosome bound by xist rna?
select all that apply.A) histone deacetylation
b) xist rna expression
C) histone acetylation
D) histone methylation
E) decondensed chromatin
F) heterochromatic
g) reduced gene expression

a) histone deacetylation
b) xist rna expression
D) histone methylation
F) heterochromatic
g) reduced gene expressionthe x-inactivation-specific transcript (xist) rna is transcribed only on the x chromosome destined to be inactivated. the xist rna prevalently coats this x chromosome, attracting histone deacetylases that remove acetyl groups and histone methyltransferases (hmts) that methylate histones.these histone modifications are hallmarks of heterochromatin, resulting in reduced/silenced gene expression and inactivation of the x chromosome. note
who the xist gene is still active.

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n drosophila, the female is the heterogametic sex.A) True
b) false

b) false

one form of hemophilia is caused by a sex-linked recessive gene. assume
who a man with hemophilia marries a phenotypically normal woman whose father had hemophilia. what is the probability that they will have a daughter with hemophilia? (note: in this problem, you must include the probability of having a daughter in your computation of the final probability.)a) 1/4
b) 1/2
c) 1/16
D) 1/8
e) 3/4

a) 1/4

one form of hemophilia is caused by a sex-linked recessive gene. assume that a man with hemophilia marries a phenotypically normal woman whose father had hemophilia. what is the probability that their first son will have hemophilia?a) 1/2
b) 1/16
C) 1/8
d) 1/4
e) 3/4

a) 1/2

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